Clinical gene therapy using recombinant adeno-associated virus vectors
نویسندگان
چکیده
منابع مشابه
Gene therapy using adeno-associated virus vectors.
SUMMARY The unique life cycle of adeno-associated virus (AAV) and its ability to infect both nondividing and dividing cells with persistent expression have made it an attractive vector. An additional attractive feature of the wild-type virus is the lack of apparent pathogenicity. Gene transfer studies using AAV have shown significant progress at the level of animal models; clinical trials have ...
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ژورنال
عنوان ژورنال: Gene Therapy
سال: 2008
ISSN: 0969-7128,1476-5462
DOI: 10.1038/gt.2008.68